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Part B4 of 8 Providing and Evaluating Care Chapter 49 of 75

Sepsis Recognition and Escalation Questions

NMC CBT sepsis practice: recognising sepsis early, the Sepsis Six within one hour, urgent escalation, and worked scenario answers.

JobLabs Editorial
By JobLabs Editorial · UK healthcare reference editorial team
· · Updated · 2 min read

Sepsis kills quickly, and it is often the nurse at the bedside who spots it first. The CBT tests two things: recognising sepsis early, and knowing that the response is fast and structured.

Think sepsis

The recognition message is simple: think sepsis in anyone with a likely infection who is deteriorating. The clues are a rising early warning score, new confusion, fever or an abnormally low temperature, fast breathing, a fast pulse, and low blood pressure. A patient with a known chest or urine infection who becomes newly confused and tachycardic is the classic exam scenario. The wrong answer is to shrug it off as “just the infection” and wait.

Escalate on suspicion

Because sepsis can progress rapidly to organ failure, you escalate urgently the moment you suspect it, rather than waiting to be certain or holding off for the ward round. Early treatment saves lives, and every hour of delay increases the risk. Acting on suspicion is not overreacting; it is the point.

The Sepsis Six

The response is a bundle delivered within the first hour of recognising sepsis, known as the Sepsis Six. It is often remembered as three in and three out.

The three given to the patient are oxygen, intravenous antibiotics, and intravenous fluids. The three taken or measured are blood cultures, lactate, and urine output. Questions here test whether you know the bundle and its one-hour window. Options that delay fluids, stop oxygen, or push the response to a later time are all wrong.

Why the hour matters

The whole design of the Sepsis Six is built around speed, because the evidence is clear that outcomes worsen with delay. This is why a nurse’s early recognition and fast escalation matter so much: they start the clock on treatment that a deteriorating septic patient cannot afford to wait for. Next: urinary catheter care. Five sepsis scenarios first.

Sources & further reading

  1. 1NICE — Sepsis: recognition, diagnosis and early managementnice.org.uk
  2. 2UK Sepsis Trust — Clinical resourcessepsistrust.org
  3. 3NMC — The Codenmc.org.uk
Key takeaway from Sepsis Recognition and Escalation Questions

Frequently asked questions

What is the Sepsis Six?
A bundle of six interventions delivered within the first hour of recognising sepsis: give high-flow oxygen, take blood cultures, give intravenous antibiotics, give intravenous fluids, measure lactate, and monitor urine output. It is often remembered as three in and three out.
How is sepsis recognised early?
Think sepsis in anyone with a likely infection who is deteriorating, especially with a rising early warning score, new confusion, fever or low temperature, fast breathing, fast pulse or low blood pressure. Early recognition and a fast response save lives.
Why is sepsis treated so urgently?
Sepsis is a life-threatening response to infection that can progress rapidly to organ failure and death. Every hour of delay in treatment increases the risk, which is why the Sepsis Six is delivered within the first hour and escalation is immediate.

Check your understanding

Quick quiz: Sepsis Recognition and Escalation Questions

5questions. Click an answer to see the explanation. Your score is saved on this device only.

  1. 1

    A patient with a chest infection becomes newly confused, feverish, with a fast pulse and rising NEWS2. What should you suspect and do?

  2. 2

    Within what timeframe should the Sepsis Six be delivered?

  3. 3

    Which of these is part of the Sepsis Six?

  4. 4

    The 'three in' of the Sepsis Six refers to which interventions?

  5. 5

    Why should a nurse who suspects sepsis not wait to be certain before escalating?

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